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Saturday, April 23, 2011


Scientist, Immunoassay Development Lead – RNAi Lead Development


Alnylam is a well established, mid-sized biotechnology company in Cambridge MA, focused on the discovery and development of RNAi therapeutics. The RNAi Lead Development (RLD) Team is seeking a highly motivated cellular immunologist or molecular biologist with proven abilities in the development, design, execution, supervision, analysis, interpretation, and communication of immunology in vitro and in vivo assays in a screening environment. The Immunoassay Development (IAD) Lead will develop, optimize, and implement medium to high throughput oligonucleotide-based immunoassays to screen a variety of candidate RNAi compounds and delivery modalities and manage a significant volume of in vitro cell biology activities

Summary of Key Responsibilities:

Responsibilities include:

  • Strategic planning and coordination of activities
  • Management of junior staff
  • Hands-on assay development and execution
  • Literature review
  • Timely delivery of presentations.

The individual will work closely with multiple project teams across various therapeutic areas.

The successful candidate will be expected to establish top-notch collaboration(s) with the goals of augmenting existing resources in support of various projects and partnerships and driving provocative, highly publishable research.


Key Requirements

  • Ph.D. in Immunology, or a related field
  • At least six years experience in immunoassay development and tissue culture
  • Expertise in in vivo modeling is highly desirable.
  • Knowledge of methods such as ELISA, ELISpot, FACS analysis, taqman and PBMC assays is required
  • Experience with medium to high throughput screening and automation preferred
  • Superior communication, organization, follow-through, and presentations skills are a must.

Alnylam Pharmaceuticals is an AA/EEO employer committed to an exciting, diverse, and enriching work environment.

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