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Thursday, May 13, 2010
Molecular Scientist positions in Hallmark Science & Technology
Scientist / Sr. Scientist who will serve an integral role developing molecular protocols for a DNA sequencing-based genetic diagnostic platform. This position will work closely with the Director of Technology to develop and automate novel sample-preparation protocols for next-generation DNA sequencing.
Duties: Transition molecular protocols from working prototypes into robust automated assays. Analyze results of next-generation sequencing-based experiments, in collaboration with the computational team when necessary. Design custom workflows on a high-throughput liquid handling robotics platform. Generate and maintain standard operating procedures for protocols developed. Prepare reports for publication and internal use, documenting techniques and methods used. Work collaboratively as part of a small, interdisciplinary team of biologists, doctors, geneticists, computer scientists, and mathematicians / statisticians. Develop new strategies for analyzing and presenting genetic sequencing data. Work efficiently in a fast-paced startup environment.
Qualifications: PhD in genetics, molecular biology, or related discipline. Proven track record developing/automating novel protocols utilizing polymerase, ligase, nuclease, and restriction enzymes. Deep mechanistic understanding of standard molecular techniques including real-time PCR, molecular cloning, DNA shearing, adapter ligation/purification. Extensive experience developing high-throughput workflows for laboratory automation. Extensive understanding of genomic technologies, including next-generation sequencing technologies and library preparation methods. Ability to independently analyze large datasets from a next-generation DNA sequencer a strong plus. Ability to perform data analysis using standard programming languages, e.g. python, perl, Matlab, in a UNIX environment a strong plus. Industry experience (e.g., product development and commercialization) a plus, especially in the clinical diagnostics space.
Scientist - Optimization
Developing molecular protocols for a DNA sequencing-based genetic diagnostic platform. This position will work closely with the Director of Technology to develop and automate novel sample-preparation protocols for next-generation DNA sequencing.
Responsibilities: Design and perform experiments to develop and optimize protocols for multiplex target capture, next-generation sequencing library preparation, and novel next-generation DNA sequencing applications. Analyze results of next-generation sequencing-based experiments, in collaboration with the computational team when new algorithms are required Design and use custom workflows on a high-throughput liquid handling robotics platform. Generate and maintain standard operating procedures for protocols developed. Prepare reports for publication and internal use, documenting techniques and methods used. Work collaboratively as part of a small, interdisciplinary team of biologists, doctors, geneticists, computer scientists, and mathematicians / statisticians. Develop new strategies for analyzing and presenting genetic sequencing data. Qualifications PhD in genetics, molecular biology, or related discipline. Strong computational analysis skills, including statistics / probability Proven track record developing novel protocols utilizing polymerase, ligase, nuclease, and restriction enzymes. Experience independently processing / analyzing large datasets from a next-generation DNA sequencer, to inform planning of follow-on experiments. Ability to perform data analysis using standard programming languages, e.g. python, perl, Matlab, in a UNIX environment. Extensive experience with standard molecular techniques including real-time PCR, molecular cloning, DNA shearing, adapter ligation/purification. Extensive understanding of genomic technologies, including next-generation sequencing technologies and library preparation methods.
For more information, contact Ken Drake, Vice President at Hallmark Science & Technology, kdrake@hallmarkit.com
Duties: Transition molecular protocols from working prototypes into robust automated assays. Analyze results of next-generation sequencing-based experiments, in collaboration with the computational team when necessary. Design custom workflows on a high-throughput liquid handling robotics platform. Generate and maintain standard operating procedures for protocols developed. Prepare reports for publication and internal use, documenting techniques and methods used. Work collaboratively as part of a small, interdisciplinary team of biologists, doctors, geneticists, computer scientists, and mathematicians / statisticians. Develop new strategies for analyzing and presenting genetic sequencing data. Work efficiently in a fast-paced startup environment.
Qualifications: PhD in genetics, molecular biology, or related discipline. Proven track record developing/automating novel protocols utilizing polymerase, ligase, nuclease, and restriction enzymes. Deep mechanistic understanding of standard molecular techniques including real-time PCR, molecular cloning, DNA shearing, adapter ligation/purification. Extensive experience developing high-throughput workflows for laboratory automation. Extensive understanding of genomic technologies, including next-generation sequencing technologies and library preparation methods. Ability to independently analyze large datasets from a next-generation DNA sequencer a strong plus. Ability to perform data analysis using standard programming languages, e.g. python, perl, Matlab, in a UNIX environment a strong plus. Industry experience (e.g., product development and commercialization) a plus, especially in the clinical diagnostics space.
Scientist - Optimization
Developing molecular protocols for a DNA sequencing-based genetic diagnostic platform. This position will work closely with the Director of Technology to develop and automate novel sample-preparation protocols for next-generation DNA sequencing.
Responsibilities: Design and perform experiments to develop and optimize protocols for multiplex target capture, next-generation sequencing library preparation, and novel next-generation DNA sequencing applications. Analyze results of next-generation sequencing-based experiments, in collaboration with the computational team when new algorithms are required Design and use custom workflows on a high-throughput liquid handling robotics platform. Generate and maintain standard operating procedures for protocols developed. Prepare reports for publication and internal use, documenting techniques and methods used. Work collaboratively as part of a small, interdisciplinary team of biologists, doctors, geneticists, computer scientists, and mathematicians / statisticians. Develop new strategies for analyzing and presenting genetic sequencing data. Qualifications PhD in genetics, molecular biology, or related discipline. Strong computational analysis skills, including statistics / probability Proven track record developing novel protocols utilizing polymerase, ligase, nuclease, and restriction enzymes. Experience independently processing / analyzing large datasets from a next-generation DNA sequencer, to inform planning of follow-on experiments. Ability to perform data analysis using standard programming languages, e.g. python, perl, Matlab, in a UNIX environment. Extensive experience with standard molecular techniques including real-time PCR, molecular cloning, DNA shearing, adapter ligation/purification. Extensive understanding of genomic technologies, including next-generation sequencing technologies and library preparation methods.
For more information, contact Ken Drake, Vice President at Hallmark Science & Technology, kdrake@hallmarkit.com
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